30 Oct 19

A clinical trial carried out in Italy confirms that twice-daily brushing with BioMin F reduces dentine hypersensitivity more effectively than conventional ‘sensitivity’ toothpaste.

A study carried out among patients in Italy has shown improvement in dentine sensitivity (DH) and high levels of satisfaction after using BioMin F after just two weeks.

Drs Stefano Daniele and Andrea Alessandri provided BioMin F to 29 patients suffering from DH, asking them to brush twice daily with the product. In addition to questions about the taste, foaming effect and texture, they were asked to report any change in DH. Over half (15 patients) reported an improvement, while 8 said it had completely resolved, 6 said it had remained the same and none believed it had become worse. A total of 19 patients (73%) said that BioMin F was more effective than other ‘sensitivity’ toothpastes they had used in the past.

The researchers were particularly impressed by one patient with severe DH, who reported a great improvement within days of starting to use BioMin, but became ill with vomiting and gastric reflux during the trial. Despite her fears that this would spark her DH again, the improvement she experienced by using BioMin F was still evident, proving that acid-resistant fluorapatite crystals had been formed to biomimetically remineralise the tooth enamel.



Fig.1: small areas of cervical loss of enamel with exposure of dentine, causing dentine hypersensitivity (DH) in response to evocative stimluli cold and air.


Fig.2: large areas of cervical loss of enamel due to powerful phenomena of abrasion and erosion of enamel and high dentine hypersensivity "DH" pain.


Following brushing with BioMin F, the particles dissolve slowly over several hours, releasing calcium, fluoride and phosphate ions to deposit fluorapatite in a unique biomimetic action. Fluorapatite is the fluoride analogue of natural tooth mineral, and remineralises the tooth enamel with a compound which is resistant to acid attack, occluding the dentine tubules and preventing the fluid flow that causes DH.


If you are interested in the study please follow the link for further information.