Clinical Studies

There are a number of on-going clinical studies on BioMin™ containing toothpaste using commercially produced materials. The first to be published is;

Clinical Studies

Gautam V and Kumar Halwai:
Comparison of Clinical Efficacy Of Four Dentifrices In the Management Of Dentinal Hypersensitivity.

IJSR - INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH Vol6. Issue-2. February 2017 ISSN no2277-8179 IF:3.508

Abstract Background:
Dentinal hypersensitivity (DH) is a painful response of a tooth to irritants such as toothbrushing, sweet or sour foods, and thermal changes. It is a cumbersome condition both for the patient and the dental care providers as well.

To compare the clinical efficacy of four different commercially available dentifrices in the management of dentinal hypersensitivity.

Materials & Methods:
A total of 160 patients clinically diagnosed with dentinal hypersensitivity (93 males and 67 females) participated in this study. The participants were randomly divided into four groups:

  • Group 1: Toothpaste containing 5% Potassium Nitrate 
  • Group 2: Toothpaste containing 5% Fluoro Calcium Phosphosilicate 
  • Group 3: Toothpaste containing 10% Strontium Chloride
  • Group 4: A herbal formulation.

The patients' DH scores for tactile, thermal, and evaporative stimuli were recorded on a visual analog scale at baseline, 2 weeks, 1 month, and 2 months.

Symptoms of dentinal hypersensitivity were reduced in all four groups.
However, group 2 showed a better clinical response.

The dentifrice containing Fluoro Calcium Phosphosilicate is more efficacious in managing dentinal sensitivity.