Clinical Studies

There are a number of on-going clinical studies on BioMin™ containing toothpaste using commercially produced materials. The first to be published is;

Clinical Studies

Gautam V and Kumar Halwai:
Comparison of Clinical Efficacy Of Four Dentifrices In the Management Of Dentinal Hypersensitivity.

IJSR - INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH Vol6. Issue-2. February 2017 ISSN no2277-8179 IF:3.508

Abstract Background:
Dentinal hypersensitivity (DH) is a painful response of a tooth to irritants such as toothbrushing, sweet or sour foods, and thermal changes. It is a cumbersome condition both for the patient and the dental care providers as well.

Aim:
To compare the clinical efficacy of four different commercially available dentifrices in the management of dentinal hypersensitivity.

Materials & Methods:
A total of 160 patients clinically diagnosed with dentinal hypersensitivity (93 males and 67 females) participated in this study. The participants were randomly divided into four groups:

  • Group 1: Toothpaste containing 5% Potassium Nitrate 
  • Group 2: Toothpaste containing 5% Fluoro Calcium Phosphosilicate 
  • Group 3: Toothpaste containing 10% Strontium Chloride
  • Group 4: A herbal formulation.

The patients' DH scores for tactile, thermal, and evaporative stimuli were recorded on a visual analog scale at baseline, 2 weeks, 1 month, and 2 months.

Results:
Symptoms of dentinal hypersensitivity were reduced in all four groups.
However, group 2 showed a better clinical response.

Conclusions:
The dentifrice containing Fluoro Calcium Phosphosilicate is more efficacious in managing dentinal sensitivity.