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BioMin® F outperforms Colgate Sensitive Pro-relief™ and Sensodyne Rapid Action™ in relieving hypersensitivity in clinical trial

SABA ARSHAD, SYED JAFFAR ABBAS ZAIDI AND WAQAS AHMED, FAROOQUI
BMC ORAL HEALTH (2021) 21:498

Method

A randomised, controlled, triple-blinded clinical trial was conducted with 140 participants clinically diagnosed with dentine hypersensitivity and randomly divided into four groups:

Group A - 5% fluorocalcium phosphosilicate (BioMin® F)

Group A

5% fluorocalcium phosphosilicate (BioMin® F)
Group B - Pro-Argin™ (Colgate Sensitive Pro-Relief™)

Group B

Pro-Argin™ (Colgate Sensitive Pro-Relief™)
Group C - 8% strontium acetate (Sensodyne Rapid Action™)

Group C

8% strontium acetate (Sensodyne Rapid Action™)
Group D - Sodium fluoride-based OTC dentifrices

Group D

Sodium fluoride-based OTC dentifrices

Sensitivity was tested with air blast, mechanical and water jet stimulion the SCHIFF cold air sensitivity scale (SCASS) and visual ana loguescale (VAS) after one minute, three days, two, four, and six weeks.


Conclusion

A total of 128 participants completed the trial.

BioMin® F showed the highest reduction in dentine hypersensitivity on SCASS and VAS for waterjet stimuli.

BioMin® F is the best long-term treatment option for managing dentine hypersensitivity.

BioMin® F outperforms Colgate Sensitive Pro-Relief™ and Sensodyne Rapid Action™ in relieving dentine hypersensitivity.